hrp0084s5.2 | Developmental Programming: Novel concepts | ESPE2015

Transgenerational Developmental Programming of Endocrine Disease

Ozanne Susan

It has been recognized for over 20 years that there is an association between patterns of early growth and long-term risk of traditionally adult onset diseases such as type 2 diabetes. This has been observed both in human epidemiological studies and in animal models. This led to the concept of the developmental origins of health and disease that suggests that the environment to which an individual is exposed during critical periods of development, such as the in utero...